Genesis 4:12 directly causes this: Cain is made a restless wanderer, so he goes out from the Lord's presence and settles in Nod.

Genesis 4:16 shows Cain becoming a fugitive in the land of Nod, fulfilling his own words in Genesis 4:14 about being a vagabond.

In Genesis 3:8, Adam and Eve hide from God after sin, echoing how Cain in Genesis 4:16 departs from God's presence as a consequence of his sin.

Genesis 2:8 identifies Eden as the garden God planted; Cain's departure is specifically from this region, marking his exile.

In 2 Kings 24:20, Judah is 'thrust from his presence' — the same exile language as Cain. National judgment echoes individual banishment from God.

In Jeremiah 23:39, God threatens to 'cast you out of my presence' — the same banishment language applied to Cain as a warning to unfaithful Israel.

In Jeremiah 52:3, Judah is 'thrust from his presence' — echoing Cain's exile. God's judgment on sin consistently means removal from his presence.

In Jonah 1:3, the prophet flees from the Lord's presence, directly mirroring Cain's departure, though for different reasons.

In 2 Thessalonians 1:9, the wicked suffer eternal exile from the Lord's presence, echoing and amplifying Cain's banishment.

In 2 Kings 13:23, God refuses to banish Israel from his presence out of covenant mercy — contrasting with Cain's swift expulsion. Both highlight what losing God's presence means.

In Job 1:12, Satan 'went out from the LORD's presence' — same phrasing as Cain's departure. Both leave God's presence, though with different purposes.

In Job 2:7, Satan again departs from God's presence to afflict Job. The shared language of leaving God's presence links fallen angel and fallen man.