In Job 6:15, Job calls friends deceitful like seasonal brooks — verse 21 echoes they are 'nothing' and afraid.

In Job 2:11-13, friends silently comforted — verse 21 now sees them as 'nothing', afraid of his suffering.

In Job 13:4, Job calls friends 'worthless physicians' — same accusation of being 'nothing' as in verse 21.

Job 19:13 continues Job's lament of estrangement from brothers and acquaintances — reinforcing the abandonment theme of Job 6:21.

Psalm 38:11 describes friends standing aloof from affliction — same as Job's friends being afraid and distant.

Proverbs 19:7 parallels Job's complaint: friends and brothers abandon the poor and needy in time of trouble.

Matthew 26:31 shows Jesus predicting disciples will scatter in fear — mirroring Job's friends who fear and abandon him in calamity.

Matthew 26:56 records disciples fleeing — same pattern of abandonment in crisis as Job's friends.

2 Timothy 4:16 recounts Paul's desertion at trial — similar to Job's friends who saw his calamity and left.

In Psalm 31:11, David also describes being an object of dread to acquaintances who flee, mirroring Job's friends' withdrawal in calamity.

Proverbs 27:10 commands not to forsake a friend in calamity, contrasting Job's friends who do exactly that.

Jeremiah 17:5 curses those who trust in man — Job experiences that as his friends prove unreliable.

Proverbs 14:20 observes that the poor are disliked by neighbors, reflecting the social rejection Job experiences from his friends.

Isaiah 2:22 warns not to trust in frail man — parallels Job's realization his friends are 'nothing' in calamity.