Genesis 17:20
And as for Ishmael, I have heard thee: Behold, I have blessed him, and will make him fruitful, and will multiply him exceedingly; twelve princes shall he beget, and I will make him a great nation.
Cross-reference
Genesis 17:6 promised Abraham kings and nations. Here God echoes that language for Ishmael — rulers and a great nation — but deliberately lesser in scope.
Genesis 16:10-12 first promised Hagar innumerable descendants and that Ishmael would live in hostility. Here God elaborates with twelve rulers and a great nation.
In Genesis 21:13, God reaffirms to Abraham that Ishmael will become a nation — echoing the 'great nation' promise made here.
In Genesis 21:18, God tells Hagar the same promise repeated here: 'I will make him into a great nation,' reassuring her at Ishmael's lowest point.
Genesis 25:12-18 lists Ishmael's twelve sons who became tribal rulers — the direct fulfillment of 'father of twelve rulers' promised here.
Genesis 21:20 shows God fulfilling this promise — 'God was with the lad' as Ishmael grows into an archer in the wilderness, beginning his path toward becoming a great nation.
Genesis 25:16 records the exact fulfillment: Ishmael's twelve princes are listed, matching the 'twelve princes' promised here.
Genesis 13:16 promised Abraham innumerable offspring like dust. Here God extends a parallel promise of multiplied descendants to Ishmael specifically.