Genesis 16:12

And he will be a wild man; his hand will be against every man, and every man’s hand against him; and he shall dwell in the presence of all his brethren.

Cross-reference

Genesis 21:20 Prophetic fulfillment

Genesis 21:20 says Ishmael 'became an archer, living in the wilderness of Paran' — a direct fulfillment of the prophecy that he'd be a wild, independent man.

Genesis 25:18 Prophetic fulfillment

Genesis 25:18 confirms the prophecy about Ishmael's descendants living in hostility, fulfilling Genesis 16:12.

In Genesis 27:40, Esau's fate parallels Ishmael's: both brothers destined for conflict and eventual independence.