Genesis 21:2 recounts the miraculous birth of Isaac to Sarah, fulfilling God's promise, summarized here.

In Genesis 21:3, Abraham names his son Isaac, the very son referred to here.

Genesis 25:26 continues the family story, recording the birth of Jacob and Esau to Isaac.

Genesis 32:28 recounts Jacob's renaming to Israel, explaining the name used in the genealogy.

Malachi 1:2-4 uses the same distinction between Esau and Jacob to declare God's sovereign love and judgment on Edom.

Matthew 1:2 continues the same line from Abraham to Isaac, linking the OT genealogy to Jesus' lineage.

Luke 3:34 also traces Jesus' lineage through Isaac, confirming the genealogical record.

Romans 9:10-13 cites the story of Isaac's sons to illustrate divine election, referencing the same patriarchal figures.

In Acts 7:8, Stephen references Isaac in the context of the covenant of circumcision, echoing the genealogy.